Table 2 Demographic, clinical and laboratory features, treatment and outcome of SLE patients with HIV
From: Human immunodeficiency virus in a cohort of systemic lupus erythematosus patients
Case | Gender | First DX | Clinical features | Autoantibodies | SLE treatment | ART | CD4 at DXa | Last CD4 | Outcome |
|---|---|---|---|---|---|---|---|---|---|
1 | F | SLE | Discoid lupus, photosensitivity, oral ulcers and arthritis | ANA and anti-Ro | CS | Yes | 434 | 337 | Good health condition, but loss of follow-up in the Rheumatology Clinic |
2 | F | SLE | Raynaud, arthritis and vasculitis | ANA, anti-dsDNA, anti-Ro and anti-La | CS | Yes | 572 | 205 | Disseminated TB at 2015, follow-up in the Infectious Diseases Clinic |
3 | F | SLE | Arthritis, leucopenia, lymphopenia, alopecia, Raynaud and photosensitivity | ANA | HCQ | Yes | 424 | 1056 | SLE in remission, HIV controlled |
4 | F | SLE | Discoid lupus, photosensitivity, nephritis, leucopenia and lymphopenia | ANA | HCQ | Yes | 149 | 524 | HCV coinfection SLE in remission and HIV controlled |
5 | F | SLE | Photosensitivity, oral ulcers, arthritis and nephritis | ANA, anti-Ro and anti-La | CS, AZA ➔ MMF and tacrolimus | Yes | 273 | 991 | Pulmonary TB in 2008, kidney transplantation in 2011 |
6 | F | SLE | Photosensitivity, serositis and arthritis | ANA | None | Yes | 172 | 391 | HCV coinfection, SLE in remission and HIV controlled |
7 | F | SLE | Alopecia, arthritis, nephritis, hemolytic anemia and hypergammaglobulinemia | ANA, anti-dsDNA and anti-Ro | HCQ, CYC ➔ AZA | Yes | 321 | 165 | Good initial response, poor adherence to treatment with posterior reactivation of nephritis and CD4 count drop |
8 | F | HIV | Hemolytic anemia, serositis, oral ulcers and arthritis | ANA, anti-Sm and anti-RNP | HCQ, MTX | Yes | NA | 477 | CMV Retinitis in 2006, SLE in remission and HIV controlled |
9 | F | HIV | Hemolytic anemia and nephritis | ANA and anti-dsDNA | CS, HCQ CYC ➔ AZA | Yes | 235 | 252 | Complete response to CYC, posterior poor adherence and loss of follow-up due to drug addiction |
10 | F | SLE | Hemolytic anemia, serositis, leucopenia, lymphopenia, oral ulcers, arthritis and nephritis | ANA and anti-dsDNA | HCQ | Yes | 203 | 323 | SLE in remission and HIV controlled |
11 | F | Both | Alopecia, hemolytic anemia, nephritis, thrombocytopenia, leucopenia and lymphopenia | ANA | CS, HCQ ➔AZA | Yes | 111 | NA | Both diagnosed in hospital stay, progressing to death from sepsis |