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Table 1 Demographic, clinical, and laboratory features of SLE patients with and without HIV infection

From: Human immunodeficiency virus in a cohort of systemic lupus erythematosus patients

Patients features

All patients (n = 602)

SLE patients without HIV

(n = 591)

SLE patients with HIV

(n = 11)

P valuea

Females

92% (602)

91.9% (591)

100% (11)

1.000

European derived

75.2% (584)

75.4% (573)

63.6% (11)

0.479

Smokingb

38.3% (582)

37.6% (215)

80% (11)

0.009

Obesity

25.3% (502)

25.9% (127)

0% (11)

0.074

Age (years)

48.2±14.9(597)

48.3±14.9 (586)

43.1±12.7 (11)

0.245

SLE age at diagnosis (years)

33.5±14.2 (591)

33.6±14.2 (580)

29.9±13.9 (11)

0.390

Malar rash

55.3% (597)

56% (586)

18.2% (11)

0.015

Photosensitivity

72.1% (598)

72.4% (587)

54.5% (11)

0.191

Oral ulcers

35.6% (598)

35.6% (587)

36.4% (11)

1.000

Arthritis

72.4% (597)

74.4% (586)

63.6% (11)

0.486

Serositis

25.2% (595)

25% (585)

36.4% (11)

0.482

Nephritis

40.9% (596)

40.5% (585)

63.6% (11)

0.134

Neurologic disorders

11.4% (596)

10.9% (585)

36.4% (11)

0.028

Psychosis

6.5% (597)

6.3% (586)

18.2% (11)

0.158

Seizures

6% (597)

6% (586)

9.1% (11)

0.498

Hematologic disorders

75.8% (598)

75.8% (587)

72.7% (11)

0.773

 Hemolytic anemia

29.1% (598)

28,6% (587)

54,5% (11)

0.089

 Leukopenia/Lymphopenia

55.9% (598)

56% (587)

45.5% (11)

0.549

 Thrombocytopenia

21.4% (598)

21.5% (587)

18.2% (11)

1.000

Anti-dsDNA

46% (567)

46% (556)

45.5% (11)

1.000

Anti-Sm

20.8% (549)

21% (538)

9.1% (11)

0.474

Anticardiolipin

27.3% (550)

27.6% (539)

9.1% (11)

0.304

Lupus Anticoagulant

10% (548)

10.1% (537)

9.1% (11)

1.000

Anti-Ro

39.9% (516)

39.4% (505)

63.6% (11)

0.125

Anti-La

13.4% (515)

13.1% (504)

27.3% (11)

0.172

Anti-RNP

31.1% (515)

31.2% (504)

27.3% (11)

1.000

SLEDAI (median)c

1 (415)

1 (407)

0 (11)

0.550

SLICC damage index (median)c

1 (559)

1 (551)

2 (11)

0.047

  1. Abbreviations: SLE systemic lupus erythematosus, SLEDAI systemic lupus erythematosus disease activity index, SLICC systemic lupus international collaborating clinics, HIV human immunodeficiency virus
  2. aChi square test for qualitative variables and Mann-Whitney test for quantitative variables
  3. bCurrent or past smoker
  4. cMedian (interquartile interval)