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Table 3 Allelic and genotype association testing results of rs1544410, rs7975232, and rs731236 in VDR for Mexican cases with osteoarthritis of the knee and controls

From: Vitamin D receptor gene polymorphisms and susceptibility for primary osteoarthritis of the knee in a Latin American population

SNP Cases
(n = 107)
n (%)
Controls
(n = 114)
n (%)
OR (CI 95%)a p
rs1544410
 Allele
  A 82 (38.0) 97 (43.0) 0.8 (0.6–1.2) 0.4
  G 132 (62.0) 131 (57.0) 1.1 (0.8–1.8) 0.4
 Genotype
  AA 4 (3.7) 9 (7.9) 0.4 (0.1–1.5) 0.2
  GA 74 (69.2) 79 (69.3) 0.9 (0.5–1.8) 0.9
  GG 29 (27.1) 26 (22.8) 1.2 (0.6–2.3) 0.5
rs7975232
 Allele
  G 112 (52.0) 115 (50.0) 1.1 (0.7–1.6) 0.7
  T 102 (48.0) 113 (50.0) 0.9 (0.6–1.4) 0.7
 Genotype
  GG 17 (15.9) 16 (14.0) 1.1 (0.5–2.4) 0.7
  GT 78 (72.9) 83 (72.8) 1.0 (0.5–1.8) 0.9
  TT 12 (11.2) 15 (13.2) 0.8 (0.3–1.9) 0.7
rs731236
 Allele
  C 35 (16.0) 55 (24.0) 0.6 (0.4–1.0) 0.04
  T 179 (84.0) 173 (76.0) 1.6 (1.0–2.6) 0.04
 Genotype
  CC 3 (2.8) 3 (2.6) 1.1 (0.2–5.4) 0.9
  CT 29 (27.1) 49 (42.9) 0.5 (0.3–0.9) 0.01
  TT 75 (70.1) 62 (54.4) 1.9 (1.1–3.4) 0.02
  1. aUnadjusted Odds ratios and 95% Confidence intervals [OR (95% CI)]