Unraveling the genetic collagen connection: clinical and therapeutic insights on genetic connective tissue disorders

Table 5 Classification of Loeys–Dietz syndrome

LDS type	Gene	OMIM [12]	Chromosome	2023 Skeletal dysplasia nosology [8]
LDS1	TGFBR1	609192	9q22	NOS 31-0030
LDS2	TGFBR2	610168	3p24	NOS 31-0040
LDS3	SMAD3	613795	15q	NOS 31-0080
LDS4	TGFB2	614816	1q41	NOS 31-0050
LDS5	TGFB3	615582	14q24	NOS 31-0060
LDS6	SMAD2	619656	18q21	NOS 31-0070

ISSN: 2523-3106