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Table 5 Cost of SLE (US$), per patient per year, according to geographic region and resource consumed

From: Characterization of the patterns of care, access, and direct cost of systemic lupus erythematosus in Brazil: findings from the Macunaíma study

Resources used

Overall

Midwest

(60)

Northeast

(60)

North

(60)

Southeast

(60)

South

(60)

p-value

Medicine (median [IQR])

910.62

[460; 4033.51]

312.8

[119.4; 937.6]

694.6

[462.4; 3712.8]

1334.5

[615.5; 4391.8]

1751.2

[654.2; 5141.5]

950.7

[489.0; 3336.3]

< 0.001

Hospitalization (median [IQR])

900.60

[382.10; 2106.41]

1891.1

[382.4; 4194.9]

430.9

[377.4; 1858.0]

1007.7

[673.0; 1182.9]

1836.0

[598.0; 3145.1]

711.2

[475.5; 1395.1]

0.29

Caregiver (median [IQR])

849.06

[283.02; 235.85]

NA [NA; NA]

283.0

[212.3; 1981.1]

424.5

[254.7; 583.7]

1202.8

[336.1; 1981.1]

1132.1

[1061.3; 1273.6]

0.336

Exams (median [IQR])

130.85

[73.70; 191.58]

38.3

[18.5; 74.8]

153.7

[117.2; 207.2]

102.6

[59.9; 174.5]

153.1

[97.6; 189.9]

187.4

[123.4; 229.4]

< 0.001

Home adaptation due to SLE (median [IQR])

70.75

[23.58; 235.85]

1179.2

[1179.2; 1179.2]

NA

[NA; NA]

235.8

[188.7; 528.3]

188.7

[117.9; 202.8]

21.2

[15.9; 35.4]

0.02

Aids and support for disability (median [IQR])

35.38

[14.15; 51.89]

82.5

[44.2; 121.5]

28.7

[16.1; 40.0]

18.9

[15.3; 40.1]

47.2

[14.2; 94.3]

14.2

[14.2; 14.2]

0.086

Consultation (median [IQR])

34.67

[23.11;

63.56]

23.1

[17.3; 34.3]

40.4

[28.9; 59.2]

34.7

[23.1; 44.0]

63.6

[37.6; 87.3]

28.9

[17.3; 52.0]

< 0.001

Transportation (median [IQR])

9.43

[5.42; 18.87]

9.4

[7.9; 18.3]

7.9

[3.3; 10.1]

6.8

[3.5; 19.1]

9.4

[9.4; 42.5]

9.4

[9.0; 18.9]

< 0.001

Total cost, per patient per year (median [IQR])

1618.51[678.66; 4601.29]

545.3

[193.0; 3246.3]

1334.1

[645.1; 4234.0]

2569.0

[927.7; 4559.3]

4036.6

[1225.5; 5971.3]

1556.5

[706.6; 3551.7]

< 0.001

  1. Sources of values 1. Brazilian health information system. Available from: http://www2.datasus.gov.br/datasus/index.php? area=02. Accessed February 12, 2021
  2. 2. Agência Nacional de Vigilância Sanitária (ANVISA). Available from: https://www.gov.br/anvisa/pt-br/assuntos/medicamentos/cmed/compras-publicas/lista-de-precos-maximos-para-compras-publicas. Accessed February 12, 2021
  3. IQR, interquartile range; NA, not applicable; SLE, systemic lupus erythematosus